Studies on inhibitors of skin-tumor promotion. Inhibitory effects of triterpenes from Cochlospermum tinctorium on Epstein-Barr virus activation.

نویسندگان

  • B Diallo
  • M Vanhaelen
  • R Vanhaelen-Fastré
  • T Konoshima
  • M Kozuka
  • H Tokuda
چکیده

Arjunolic acid, an oleanene-type triterpene isolated from the rhizome of Cochlospermum tinctorium, its triacetate derivative, and their methyl esters were tested using the short-term in vitro assay on EBV-EA activation in Raji cells induced by 12-O-tetradecanoyl-phorbol-13-acetate (TPA). Their inhibitory effects on skin tumor promotors were found to be greater than those of previously studied natural products.

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عنوان ژورنال:
  • Journal of natural products

دوره 52 4  شماره 

صفحات  -

تاریخ انتشار 1989